Research groups at the Department of Neuroscience study different aspects of the function of the normal nervous system, as well as disturbances, injuries and diseases affecting the nervous system. Projects include a broad range of studies at the molecular and cellular levels, the network level and at the level of the overall organization of the nervous system.

The department also conducts undergraduate education in neuroscience, anatomy and histology in a number of programs at Karolinska Institutet. To read more about our department, please visit our webpage; www.ki.se/en/neuro/startpage

Duties

The position is part of the research program in genetics and neurological diseases and within this program, the senior researcher is expected to focus on cluster headache and related disorders.

The aim is to identify genetic risk and protective factors in cluster headache, to understand the role of identified candidate genes by studying where and how the gene is expressed in human and rodent tissue, and to identify any differences in gene expression between diseased and healthy individuals through the study of biological tissue. When possible, findings should be followed up by the development genetic animal models. Research will be based on clinical material collected from patients with cluster headache and controls in collaboration with clinicians at the Neurology clinic, Karolinska University Hospital.

Genetic and clinical data are entered into databases, hence experience in the analysis of large data sets, as from e.g. genome wide association studies, is important. The successful applicant will be responsible for the research program's growing biobank of DNA samples and related cell lines, and independently perform analysis, compile data in databases, and be responsible for the writing of scientific reports.

The applicant is expected to conduct her/his own successful research, and the documentation of own experiences as main supervisor of PhD students who has successfully finished their thesis is an advantage. He/she will also be the biobank manager at the Department of Neuroscience. The successful applicant is expected to seek external funding from Swedish and foreign organizations.

Entry requirements

A person is eligible to be appointed Senior Researcher if he or she has been awarded a Degree of Doctor or has achieved the corresponding scientific competence, as well as documented research after publicly defending his or her doctoral thesis corresponding to qualification as Assistant professor.

Applicants must have proven experience of independently conducted genetic research. Experience of working with molecular biology techniques, in situ hybridization and behavioral studies, preferably in the field of neurobiology, is a requirement. Experience of working with large data sets and analysis using the statistical program GraphPad is also a requirement. Experience in national and international collaborative networks is a merit.

Applicants should have a degree in biomedicine. He/she is expected to cooperate in national and international networks, so experience of working in research networks and professional command of English language are requirements. The scientific breadth of the employment requires good cooperation and communication skills. The applicant must be organized, meticulous, motivated and a skilled problem solver. Applicants must have completed a PhD and be a docent or document skills equivalent to a docent.

Furthermore, the following qualifications are required:

- Experience as a group leader Experience in supervising Postdocs Completed animal training (laboratory animal science course)

- Postgraduate supervisor training course to have the ability to supervise PhD students

- Track record in acquiring research fundi

Timmar per vecka:
Full time. Tillträde: as soon as possible tillsvidareanställning

Arbetsgivare Namn:
Karolinska Institutet, Department of Neuroscience, Olson

Arbetsgivare adress: Retzius väg 8 17177 Solna

Form av kontakt:
Anne Edgren, OFR/S, P, O titel : telefon 1: 08-616 16 29() telefon 2: () mobil: e-post:

Jobb kort beskrivning: University and higher education teachers

Land: Sweden

Område: Stockholms län

Avtalstid: Permanent

Typ av kontrakt: Full time

Källa till jobberbjudande: Public Employment Service of Sweden(AMS)

Hur man ansöker: Other - see free text